Conference Proceedings
Genetic and Environmental Influences on Language Ability in Older Adults: Findings from the Older Australian Twins Study
T Lee, A Thalamuthu, JD Henry, JN Trollor, D Ames, MJ Wright, PS Sachdev
Behavior Genetics | SPRINGER | Published : 2018
Abstract
We used a sub-sample from the Older Australian Twins Study to estimate the heritability of performance on three tests of language ability: Boston Naming Test (BNT), Letter/Phonemic Fluency (FAS) and Category/Semantic Fluency (CFT) Tests. After adjusting for age, sex, education, mood, and global cognition (GC), heritability estimates obtained for the three tests were 0.35, 0.59, and 0.20, respectively. Multivariate analyses showed that the genetic correlation were high for BNT and CFT (0.61), but low for BNT and FAS (0.17), and for FAS and CFT (0.28). Genetic modelling with Cholesky decomposition indicated that the covariation between the three measures could be explained by a common genetic ..
View full abstractGrants
Awarded by National Health and Medical Research Council
Funding Acknowledgements
The Older Australian Twins Study was supported by the National Health and Medical Research Council (NHMRC, ID No. 401162).